Slowing Down the Progression of Memory Loss

PROLINE-RICH POLYPEPTIDES IN FIRST-MILKING COLOSTRUM AID COGNITIVE HEALTH
you’ve probably never heard of the
ultra-tiny amino-acid sequence called
proline-rich polypeptide (PRP). But
39 studies published on PubMed
(www.pubmed.com) that talk about
PRPs suggest these wunderkinds are
truly a breakthrough in anti-aging medicine,
immune health and mind power.
Technically speaking, PRPs, isolated
from first-milking colostrum, are aminoacid
sequences of ten chains or fewer of
high amounts of proline. Though small,
they are critical to healthy immune function
and activate the thymus gland.
With enhanced immune activity via
thymus-gland function, the body is able
to not only fight off viral and bacterial
infections, but also down-regulate inflammatory
pathways within the normal range. Now researchers
have found that PRPs offer a safe and promising
preventive approach for fighting off symptoms of
memory loss, including possibly Alzheimer’s. However,
we must hasten to add that PRPs are not drugs
and not intended to treat, cure or diagnose any disease.
They are part of first-milking colostrum and
there to help your body maintain and support memory
and mental activity.
Bio-Medicine reported on July 29, 2005,
“Based on findings of a recent study, researchers
say that a mixture of peptides derived from
colostrum could help slow the progression of
Alzheimer’s disease by reducing the buildup of
beta amyloid, a toxic protein that accumulates in
the brains of Alzheimer’s sufferers.” The report
noted, “In a double-blind, placebo-controlled trial
on 106 people with mild to moderate Alzheimer’s
disease published last year, it was found that after
15 weeks of taking the product in tablet form,
around 40 percent of the patients were stabilized or
had an improved overall response in tests on cognitive
function. The greatest effects were seen during
the earlier stages of the disease, and no serious
adverse events were observed during the trial.”
In the latest study, published in the July 2009
issue of the Journal of Nutrition, Health & Aging
(13;6:522-7), researchers established that it had
previously been demonstrated that oral administration
of proline-rich polypeptide isolated from
colostrum “can effectively treat Alzheimer’s disease
patients,” and in this recent article, they observed
that neuronal cells pretreated with PRPs avoid the
accumulation of beta amyloid.
A review article in the October 1, 2007 issue of
Progress in Neuro-Psychopharmacology & Biological
Psychiatry (31;7:1347-55) further supported
these findings. Dr. A. Gladkevich of the Department
of Psychiatry, University of Groningen, the Netherlands,
noted the growing body of work on PRPs,
saying “The development of effective and safe
drugs for a growing Alzheimer-disease population
is an increasing need at present. Both experimental
and clinical evidence support a beneficial effect
of PRPs in a number of neurodegenerative diseases,
including Alzheimer disease. Experimental
data have shown that proline-rich polypeptides isolated
from bovine neurohypophysis possess neuroprotective
and neuromodulatory properties in mice
with aluminum neurotoxicosis or neuronal damage
caused by venoms and toxins.”
PRPs because, compared to New Zealand
Colostrum and other similar products, it is only collected
from the first milking that occurs within eight
hours of the birth of the calf. New Zealand
Colostrums can be collected 24 hours or more after
the birth, at which time the levels of growth factors
and peptides are far more reduced.
Cognitive improvements are one of the first
things that patients who use Immune-Tree certified
colostrums experience.
Of course, Immune-Tree certified first-milking
colostrum is not a drug but a food that should be
used for the maintenance of healthy mental function.
Interestingly, special transport molecules in
colostrum actually shield PRPs from degradation in
the stomach so they can pass through into systemic
circulation. Besides its promising benefits for cognitive
health and mental function, first-milking
colostrum is one of the most effective methods of
maintaining immune health and helps to add muscle,
normalize allergic responses, and up- or downregulate
the immune system. Much of this is thanks
to PRPs, those amazing ultra-tiny molecules, and
now they’re available in a formula that holds real
promise for those who might benefit most.

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